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AGKISTRODON RHODOSTOMA VENOM PROTEASE
Descriptors Found:
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DeCS
Descriptor
English
:
Ancrod
Descriptor
Spanish
:
Ancrod
Descriptor
Portuguese
:
Ancrod
Synonyms
English
:
Arvin
Arvin IRC-50
Arwin
Venacil
Arvin IRC 50
Arvin IRC50
Agkistrodon rhodostoma Venom Protease
Agkistrodon Serine Proteinase
Tree Number:
D08.811.277.656.300.760.955.060
D08.811.277.656.959.350.955.060
D20.888.850.960.200.050
D23.946.833.850.960.200.050
Definition
English
:
An enzyme fraction from the venom of the Malayan pit viper,
Agkistrodon
rhodostoma. It catalyzes the
hydrolysis
of a number of amino acid
esters
and a limited
proteolysis
of
fibrinogen
. It is used clinically to produce controlled defibrination in
patients
requiring anticoagulant therapy. EC 3.4.21.-.
Pharmacological Action:
Anticoagulants
Fibrinolytic Agents
History Note
English
:
78; was ARVIN see under ENDOPEPTIDASES 1975-77; ARVIN was see ANCROD 1978-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23155
Unique Identifier:
D000721
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS